REPOST: Examining embryonic teeth prevents problems in later life

A new study being discussed in The Digital Journal shows how a groundbreaking imaging technique could help prevent future teeth and jaw problems using embryo samples.

Image Source: digitaljournal.com

A new 3D imaging technique shows how to prevent teeth and jaw problems through early intervention. This is by identifying incoming wisdom teeth, crowded teeth, and malocclusion in the embryo. 

 

Working with scientists on the Biomedical Imaging and Therapy (BMIT) beamline at the Canadian Light Source synchrotron, a research group from the University of Saskatchewan observed, in microscopic detail, the 3D organization of young teeth within the jaw. The findings lay the groundwork and could have future impact on oral health-related quality of life. 

 

To test out the method scientists used a synchrotron-based micro-computed tomography (micro-CT) imaging technique, according to the Oral Health Group. With the method, silver-stained mouse embryo samples showed even the very earliest stages of tooth development. This type of 3D imaging technique for teeth is rare because of the technical specifications required to maximize the scanner so that it can capture such tiny, translucent and jelly-like tissues. The success on animal models will lead to trials on humans next.

 

The research was recently published in The Anatomical Record. The paper is titled "Technique: imaging earliest tooth development in 3D using a silver-based tissue contrast agent."

The study was undertaken at the Canadian Light Source. This is Canada’s national centre for synchrotron research and a global centre of excellence in synchrotron science and its applications. Located on the University of Saskatchewan campus in Saskatoon, the CLS has hosted 1,700 researchers from academic institutions, government, and industry from 10 provinces and territories; delivered over 26,000 experimental shifts; received over 6,600 user visits; and provided a scientific service critical in over 1,000 scientific publications, since beginning operations in 2005.

 Support for this research was provided by the Natural Sciences and Engineering Research Council of Canada and the Canadian Institutes of Health Research - THRUST program.

Dr. Domenick Coletti is an expert oral and maxillofacial surgeon practicing in Maryland. Learn more about the latest procedures and treatments of oral health problems by following this Twitter account.